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IgH partner breakpoint sequences provide evidence that AID initiates t(11;14) and t(8;14) chromosomal breaks in mantle cell and Burkitt lymphomas

Previous studies have implicated activation-induced cytidine deaminase (AID) in B-cell translocations but have failed to identify any association between their chromosomal breakpoints and known AID target sequences. Analysis of 56 unclustered IgH-CCND1 translocations in mantle cell lymphoma across t...

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Hlavní autoři: Greisman, Harvey A., Lu, Zhengfei, Tsai, Albert G., Greiner, Timothy C., Yi, Hye Son, Lieber, Michael R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466967/
https://ncbi.nlm.nih.gov/pubmed/22915650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-02-412791
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