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Erroneous class switching and false VDJ recombination: Molecular dissection of t(8;14)/MYC‐IGH translocations in Burkitt‐type lymphoblastic leukemia/B‐cell lymphoma
The chromosomal translocation t(8;14)(q24;q32) with juxtaposition of MYC to enhancer elements in the immunoglobulin heavy chain (IGH) gene locus is the genetic hallmark of the majority of Burkitt lymphoma and a subset of Diffuse large B‐cell lymphoma patients. Around 3% of adult B‐lineage acute lymp...
Shranjeno v:
| izdano v: | Mol Oncol |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
John Wiley and Sons Inc.
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5528421/ https://ncbi.nlm.nih.gov/pubmed/23673335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2013.04.006 |
| Oznake: |
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