5-Azacytidine stimulates fetal hemoglobin synthesis in anemic baboons.
In an attempt to stimulate Hb F synthesis in baboons by means other than erythropoietic stress, we considered the possibility that an agent that inhibits methylation of CpG sequences in DNA may be effective. 5-Azacytidine, a cytosine analogue that cannot be methylated, is such an agent. Animals whos...
Збережено в:
| Опубліковано в:: | Proc Natl Acad Sci U S A |
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| Автори: | , , , |
| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
National Academy of Sciences
1982
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| Предмети: | |
| Онлайн доступ: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346685/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6181507/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.14.4428 |
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