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5-Azacytidine stimulates fetal hemoglobin synthesis in anemic baboons.

In an attempt to stimulate Hb F synthesis in baboons by means other than erythropoietic stress, we considered the possibility that an agent that inhibits methylation of CpG sequences in DNA may be effective. 5-Azacytidine, a cytosine analogue that cannot be methylated, is such an agent. Animals whos...

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Detalhes bibliográficos
Main Authors: DeSimone, J, Heller, P, Hall, L, Zwiers, D
Formato: Artigo
Idioma:Inglês
Publicado em: 1982
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC346685/
https://ncbi.nlm.nih.gov/pubmed/6181507
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