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Further investigation of the light chain shifting phenomenon: Light chain replacement through secondary rearrangement induced by lectin stimulation in the hybridoma cell line HB4C5

We found that when the hybridoma cell line HB4C5 was stimulated with wheat germ agglutinin (WGA), loss of production of the original λ light chain occurred, followed by production of new light chain, which mirrored the reaction when stimulated with concanavalin A (ConA). We previously reported that...

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Detalhes bibliográficos
Main Authors: Krungkasem, Chatchadaporn, Ueda, Kyoko, Tachibana, Hirofumi, Shirahata, Sanetaka
Formato: Artigo
Idioma:Inglês
Publicado em: Kluwer Academic Publishers 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466735/
https://ncbi.nlm.nih.gov/pubmed/9474807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1023/A:1007943228587
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