Ex vivo Mimicry of Normal and Abnormal Human Hematopoiesis

Hematopoietic stem cells require a unique microenvironment in order to sustain blood cell formation(1); the bone marrow (BM) is a complex three-dimensional (3D) tissue wherein hematopoiesis is regulated by spatially organized cellular microenvironments termed niches(2-4). The organization of the BM...

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Bibliographic Details
Main Authors: Mortera-Blanco, Teresa, Rende, Maria, Macedo, Hugo, Farah, Serene, Bismarck, Alexander, Mantalaris, Athanasios, Panoskaltsis, Nicki
Format: Artigo
Language:Inglês
Published: MyJove Corporation 2012
Subjects:
Bioengineering
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466659/
https://ncbi.nlm.nih.gov/pubmed/22525832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/3654
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