Human telomerase reverse transcriptase (hTERT) is a target gene of β-catenin in human colorectal tumors

The majority of colorectal cancers (CRCs) are characterized by a dysregulated canonical Wnt-signaling pathway leading to the stabilization and subsequent cellular increase and accumulation of β-catenin. After translocation into the nucleus, it acts as a transcription factor resulting in the expressi...

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Bibliographic Details
Main Authors: Jaitner, Stefanie, Reiche, Jana A., Schäffauer, Achim J., Hiendlmeyer, Elke, Herbst, Hermann, Brabletz, Thomas, Kirchner, Thomas, Jung, Andreas
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466531/
https://ncbi.nlm.nih.gov/pubmed/22894902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.21790
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