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Human telomerase reverse transcriptase (hTERT) is a target gene of β-catenin in human colorectal tumors
The majority of colorectal cancers (CRCs) are characterized by a dysregulated canonical Wnt-signaling pathway leading to the stabilization and subsequent cellular increase and accumulation of β-catenin. After translocation into the nucleus, it acts as a transcription factor resulting in the expressi...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Landes Bioscience
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3466531/ https://ncbi.nlm.nih.gov/pubmed/22894902 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.21790 |
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