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The role of S6K1 in ER-positive breast cancer

The 40S ribosomal S6 kinase 1 (S6K1) is a conserved serine/threonine protein kinase that belongs to the AGC family of protein kinases, which also includes Akt and many others. S6K1 is the principal kinase effector downstream of the mammalian target of rapamycin complex 1 (mTORC1). S6K1 is sensitive...

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Detalhes bibliográficos
Autor principal: Holz, Marina K.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466514/
https://ncbi.nlm.nih.gov/pubmed/22895181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.21194
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