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Immunochemical analysis of the glucocorticoid receptor: identification of a third domain separate from the steroid-binding and DNA-binding domains.

The glucocorticoid-receptor complex can be subdivided into three separate domains by limited proteolysis with trypsin or alpha-chymotrypsin. The following characteristics can be separated: steroid-binding activity (domain A), DNA-binding activity (domain B), and immunoactivity (domain C). We have pr...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Carlstedt-Duke, J, Okret, S, Wrange, O, Gustafsson, J A
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1982
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346650/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6181503/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.14.4260
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