Purified glucocorticoid receptors bind selectively in vitro to a cloned DNA fragment that mediates a delayed secondary response to glucocorticoids in vivo.

We have identified and characterized a 206-base-pair region downstream from rat alpha 2u-globulin promoter that specifically mediates a delayed secondary response to glucocorticoids. Unlike positive primary glucocorticoid response elements (GREs), this regulatory element, termed delayed sGRE, dictat...

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Bibliographic Details
Main Authors: Hess, P, Meenakshi, T, Chan, G C, Carlstedt-Duke, J, Gustafsson, J A, Payvar, F
Format: Artigo
Language:Inglês
Published: 1990
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC53730/
https://ncbi.nlm.nih.gov/pubmed/1690888
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