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The role of glycogen synthase kinase-3 signaling in neurodevelopment and fragile X syndrome

Fragile X syndrome (FXS), one of the most common genetic causes of autism, results from a loss of fragile X mental retardation protein (FMRP) expression. At the molecular level, abnormal neurodevelopment is thought to result from dysregulated protein synthesis of key neural synaptic proteins, howeve...

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Autori principali: Portis, Samantha, Giunta, Brian, Obregon, Demian, Tan, Jun
Natura: Artigo
Lingua:Inglês
Pubblicazione: e-Century Publishing Corporation 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466494/
https://ncbi.nlm.nih.gov/pubmed/23071871
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