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Lithium ameliorates altered glycogen synthase kinase-3 and behavior in a mouse model of Fragile X syndrome

Fragile X syndrome (FXS), the most common form of inherited mental retardation and a genetic cause of autism, results from mutated fragile X mental retardation-1 (Fmr1). This study examined the effects on glycogen synthase kinase-3 (GSK3) of treatment with a metabotropic glutamate receptor (mGluR) a...

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Detalhes bibliográficos
Main Authors: Yuskaitis, Christopher J., Mines, Marjelo A., King, Margaret K., Sweatt, J. David, Miller, Courtney A., Jope, Richard S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810609/
https://ncbi.nlm.nih.gov/pubmed/19799873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2009.09.023
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