Dimebon alters hippocampal amyloid pathology in 3xTg-AD mice

A double blind, placebo-controlled phase II study revealed that the antihistamine, Dimebon® (dimebolin, latrepirdine) improved cognition in Alzheimer disease (AD) patients compared to placebo controls. However, the Phase III CONNECTION trial failed to demonstrate significant differences between dime...

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Autors principals: Perez, Sylvia E, Nadeem, Muhammad, Sadleir, Katherine R, Matras, Joanna, Kelley, Christy M, Counts, Scott E, Vassar, Robert, Mufson, Elliott J
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2012
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466490/
https://ncbi.nlm.nih.gov/pubmed/23071869
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