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Antigenic strength controls the generation of antigen-specific IL-10-secreting T regulatory cells
Administration of peptides i.n. induces peripheral tolerance in Tg4 myelin basic protein-specific TCR-Tg mice. This is characterized by the generation of anergic, IL-10-secreting CD4(+) T cells with regulatory function (IL-10 Treg). Myelin basic protein Ac1–9 peptide analogs, displaying a hierarchy...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3466465/ https://ncbi.nlm.nih.gov/pubmed/20162554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200940151 |
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