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NADPH oxidase modulates MHC class II antigen presentation by B cells

Phagocyte NADPH oxidase plays a key role in pathogen clearance via reactive oxygen species (ROS) production. Defects in oxidase function result in chronic granulomatous disease (CGD) with hallmark recurrent microbial infections and inflammation. The oxidase′s role in the adaptive immune response is...

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Autori principali: Crotzer, Victoria L., Matute, Juan D., Arias, Andrés A., Zhao, Heng, Quilliam, Lawrence A., Dinauer, Mary C., Blum, Janice S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466399/
https://ncbi.nlm.nih.gov/pubmed/22984083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103080
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