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LAMP-2-deficient human B cells exhibit altered MHC class II presentation of exogenous antigens

Major histocompatibility complex (MHC) class II molecules present antigenic peptides derived from engulfed exogenous proteins to CD4(+) T cells. Exogenous antigens are processed in mature endosomes and lysosomes where acidic proteases reside and peptide-binding to class II alleles is favoured. Hence...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Crotzer, Victoria L, Glosson, Nicole, Zhou, Delu, Nishino, Ichizo, Blum, Janice S
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Blackwell Science Inc 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996552/
https://ncbi.nlm.nih.gov/pubmed/20518820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2010.03309.x
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