A randomized clinical trial of the effects of supplemental calcium and vitamin D(3) on the APC/β-catenin pathway in the normal mucosa of colorectal adenoma patients

APC/β-catenin pathway perturbation is a common early event in colorectal carcinogenesis and is affected by calcium and vitamin D in basic science studies. To assess the effects of calcium and vitamin D on APC, β-catenin, and E-cadherin expression in the normal appearing colorectal mucosa of sporadic...

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Hauptverfasser: Ahearn, Thomas U., Shaukat, Aasma, Flanders, W. Dana, Rutherford, Robin E., Bostick, Roberd M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466388/
https://ncbi.nlm.nih.gov/pubmed/22964475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-12-0292
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