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Predicting the Functional Effect of Amino Acid Substitutions and Indels

As next-generation sequencing projects generate massive genome-wide sequence variation data, bioinformatics tools are being developed to provide computational predictions on the functional effects of sequence variations and narrow down the search of casual variants for disease phenotypes. Different...

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Detalhes bibliográficos
Main Authors: Choi, Yongwook, Sims, Gregory E., Murphy, Sean, Miller, Jason R., Chan, Agnes P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466303/
https://ncbi.nlm.nih.gov/pubmed/23056405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046688
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