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The Combined Effects of Amino Acid Substitutions and Indels on the Evolution of Structure within Protein Families

BACKGROUND: In the process of protein evolution, sequence variations within protein families can cause changes in protein structures and functions. However, structures tend to be more conserved than sequences and functions. This leads to an intriguing question: what is the evolutionary mechanism by...

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Bibliografske podrobnosti
Main Authors: Zhang, Zheng, Wang, Yuxiao, Wang, Lushan, Gao, Peiji
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001449/
https://ncbi.nlm.nih.gov/pubmed/21179197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014316
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