Dimethylfumarate Attenuates Renal Fibrosis via NF-E2-Related Factor 2-Mediated Inhibition of Transforming Growth Factor-β/Smad Signaling

TGF-β plays a key role in the development of renal fibrosis. Suppressing the TGF-β signaling pathway is a possible therapeutic approach for preventing this disease, and reports have suggested that Nrf2 protects against renal fibrosis by inhibiting TGF-β signaling. This study examines whether dimethy...

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Main Authors: Oh, Chang Joo, Kim, Joon-Young, Choi, Young-Keun, Kim, Han-Jong, Jeong, Ji-Yun, Bae, Kwi-Hyun, Park, Keun-Gyu, Lee, In-Kyu
格式: Artigo
語言:Inglês
出版: Public Library of Science 2012
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466265/
https://ncbi.nlm.nih.gov/pubmed/23056222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045870
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