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Structure activity studies of RNA-binding oxazolidinone derivatives

The structure activity relationship of a series of oxazolidinones binding to T-box riboswitch antiterminator RNA has been investigated. Oxazolidinones differentially substituted at C-5 were prepared and the ligand-induced fluorescence resonance energy transfer (FRET) changes in FRET-labeled antiterm...

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Detalhes bibliográficos
Main Authors: Maciagiewicz, Iwona, Zhou, Shu, Bergmeier, Stephen C., Hines, Jennifer V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466080/
https://ncbi.nlm.nih.gov/pubmed/21733684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2011.05.130
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