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A Library of 1,4-Disubstituted 1,2,3-Triazole Analogs of Oxazolidinone RNA-Binding Agents

The design and synthesis of small molecules that target RNA is immensely important in antibacterial therapy. We had previously reported on the RNA binding of a series of 4,5-disubstituted 2-oxazolidinones that bind to a highly conserved bulge region of bacterial RNA. This biological target T box ant...

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Detalhes bibliográficos
Main Authors: Acquaah-Harrison, George, Zhou, Shu, Hines, Jennifer V., Bergmeier, Stephen C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925680/
https://ncbi.nlm.nih.gov/pubmed/20557032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cc100029y
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