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Biochemical and pharmacological characterization of human α/β-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12)

In the central nervous system, three enzymes belonging to the serine hydrolase family are thought to regulate the life time of the endocannabinoid 2-arachidonoylglycerol (C20:4) (2-AG). From these, monoacylglycerol lipase (MAGL) is well characterized and, on a quantitative basis, is the main 2-AG hy...

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Bibliografiske detaljer
Main Authors: Navia-Paldanius, Dina, Savinainen, Juha R., Laitinen, Jarmo T.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466009/
https://ncbi.nlm.nih.gov/pubmed/22969151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M030411
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