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Regulation of the human prostacyclin receptor gene by the cholesterol-responsive SREBP1

Prostacyclin and its prostacyclin receptor, the I Prostanoid (IP), play essential roles in regulating hemostasis and vascular tone and have been implicated in a range cardio-protective effects but through largely unknown mechanisms. In this study, the influence of cholesterol on human IP [(h)IP] gen...

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Autori principali: Turner, Elizebeth C., Kinsella, B. Therese
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466007/
https://ncbi.nlm.nih.gov/pubmed/22969152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M029314
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