Interaction of the Human Prostacyclin Receptor with Rab11: CHARACTERIZATION OF A NOVEL Rab11 BINDING DOMAIN WITHIN α-HELIX 8 THAT IS REGULATED BY PALMITOYLATION

The human prostacyclin receptor (hIP) undergoes agonist-induced internalization and subsequent recyclization in slowly recycling endosomes involving its direct physical interaction with Rab11a. Moreover, interaction with Rab11a localizes to a 22-residue putative Rab11 binding domain (RBD) within the...

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Autors principals: Reid, Helen M., Mulvaney, Eamon P., Turner, Elizebeth C., Kinsella, B. Therese
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2010
Matèries:
Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881795/
https://ncbi.nlm.nih.gov/pubmed/20395296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.106476
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