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Simultaneous activation of p38 and JNK by arachidonic acid stimulates the cytosolic phospholipase A(2)-dependent synthesis of lipid droplets in human monocytes

Exposure of human peripheral blood monocytes to free arachidonic acid (AA) results in the rapid induction of lipid droplet (LD) formation by these cells. This effect appears specific for AA in that it is not mimicked by other fatty acids, whether saturated or unsaturated. LDs are formed by two diffe...

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Autores principales: Guijas, Carlos, Pérez-Chacón, Gema, Astudillo, Alma M., Rubio, Julio M., Gil-de-Gómez, Luis, Balboa, María A., Balsinde, Jesús
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Biochemistry and Molecular Biology 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466003/
https://ncbi.nlm.nih.gov/pubmed/22949356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M028423
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