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Structure of Staphylococcus aureus EsxA suggests a contribution to virulence by action as a transport chaperone and/or adaptor protein

Staphylococcus aureus pathogenesis depends on a specialized protein secretion system, ESX-1, that delivers a range of virulence factors to assist infectivity. We report the characterization of two such factors, EsxA and EsxB; small acidic dimeric proteins carrying a distinctive WXG motif. EsxA cryst...

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Detalhes bibliográficos
Main Authors: Sundaramoorthy, Ramasubramanian, Fyfe, Paul K., Hunter, William N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465917/
https://ncbi.nlm.nih.gov/pubmed/18773907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.08.047
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