Exenatide Pretreatment Improved Graft Function in Nonhuman Primate Islet Recipients Compared to Treatment after Transplant Only

The GLP-1 receptor agonist, exenatide, has previously been shown to improve insulin secretion, protect beta cells from apoptosis, and promote beta cell regeneration. We propose that pretreatment with exenatide will promote islet graft survival and improve graft function. Pancreatectomized cynomolgus...

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Detalhes bibliográficos
Main Authors: Buss, Jill L., Rajab, Amer, Essig, Elizabeth D., Bergdall, Valerie K., Wang, Jie, Osei, Kwame
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465909/
https://ncbi.nlm.nih.gov/pubmed/23056916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/382518
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