Synthetic Archaeosome Vaccines Containing Triglycosylarchaeols Can Provide Additive and Long-Lasting Immune Responses That Are Enhanced by Archaetidylserine

The relation between archaeal lipid structures and their activity as adjuvants may be defined and explored by synthesizing novel head groups covalently linked to archaeol (2,3-diphytanyl-sn-glycerol). Saturated archaeol, that is suitably stable as a precursor for chemical synthesis, was obtained in...

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Autors principals: Sprott, G. Dennis, Yeung, Angela, Dicaire, Chantal J., Yu, Siu H., Whitfield, Dennis M.
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2012
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465877/
https://ncbi.nlm.nih.gov/pubmed/23055819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/513231
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