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Synthetic Archaeosome Vaccines Containing Triglycosylarchaeols Can Provide Additive and Long-Lasting Immune Responses That Are Enhanced by Archaetidylserine

The relation between archaeal lipid structures and their activity as adjuvants may be defined and explored by synthesizing novel head groups covalently linked to archaeol (2,3-diphytanyl-sn-glycerol). Saturated archaeol, that is suitably stable as a precursor for chemical synthesis, was obtained in...

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Bibliografiske detaljer
Main Authors: Sprott, G. Dennis, Yeung, Angela, Dicaire, Chantal J., Yu, Siu H., Whitfield, Dennis M.
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465877/
https://ncbi.nlm.nih.gov/pubmed/23055819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/513231
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