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Age-associated inflammation inhibits epidermal stem cell function

Altered stem cell homeostasis is linked to organismal aging. However, the mechanisms involved remain poorly understood. Here we report novel alterations in hair follicle stem cells during skin aging, including increased numbers, decreased function, and an inability to tolerate stress. Performing hig...

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Detalhes bibliográficos
Main Authors: Doles, Jason, Storer, Mekayla, Cozzuto, Luca, Roma, Guglielmo, Keyes, William M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465736/
https://ncbi.nlm.nih.gov/pubmed/22972935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.192294.112
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