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Age-associated inflammation inhibits epidermal stem cell function

Altered stem cell homeostasis is linked to organismal aging. However, the mechanisms involved remain poorly understood. Here we report novel alterations in hair follicle stem cells during skin aging, including increased numbers, decreased function, and an inability to tolerate stress. Performing hig...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Doles, Jason, Storer, Mekayla, Cozzuto, Luca, Roma, Guglielmo, Keyes, William M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465736/
https://ncbi.nlm.nih.gov/pubmed/22972935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.192294.112
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