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Exploring the gap between dynamic and constraint-based models of metabolism

Systems biology provides new approaches for metabolic engineering through the development of models and methods for simulation and optimization of microbial metabolism. Here we explore the relationship between two modeling frameworks in common use namely, dynamic models with kinetic rate laws and co...

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Detalhes bibliográficos
Main Authors: Machado, Daniel, Costa, Rafael S., Ferreira, Eugénio C., Rocha, Isabel, Tidor, Bruce
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465724/
https://ncbi.nlm.nih.gov/pubmed/22306209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymben.2012.01.003
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