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Membrane Fission Is Promoted by Insertion of Amphipathic Helices and Is Restricted by Crescent BAR Domains

Shallow hydrophobic insertions and crescent-shaped BAR scaffolds promote membrane curvature. Here, we investigate membrane fission by shallow hydrophobic insertions quantitatively and mechanistically. We provide evidence that membrane insertion of the ENTH domain of epsin leads to liposome vesiculat...

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Detalhes bibliográficos
Main Authors: Boucrot, Emmanuel, Pick, Adi, Çamdere, Gamze, Liska, Nicole, Evergren, Emma, McMahon, Harvey T., Kozlov, Michael M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465558/
https://ncbi.nlm.nih.gov/pubmed/22464325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.01.047
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