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Membrane Fission Is Promoted by Insertion of Amphipathic Helices and Is Restricted by Crescent BAR Domains

Shallow hydrophobic insertions and crescent-shaped BAR scaffolds promote membrane curvature. Here, we investigate membrane fission by shallow hydrophobic insertions quantitatively and mechanistically. We provide evidence that membrane insertion of the ENTH domain of epsin leads to liposome vesiculat...

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Hlavní autoři: Boucrot, Emmanuel, Pick, Adi, Çamdere, Gamze, Liska, Nicole, Evergren, Emma, McMahon, Harvey T., Kozlov, Michael M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cell Press 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465558/
https://ncbi.nlm.nih.gov/pubmed/22464325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.01.047
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