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Treatment of Oseltamivir-Resistant Influenza A (H1N1) Virus Infections in Mice With Antiviral Agents

Influenza A/Mississippi/03/2001 (H1N1) and A/Hong Kong/2369/2009 (H1N1) viruses containing the neuraminidase gene mutation H275Y (conferring resistance to oseltamivir) were adapted to mice and evaluated for suitability as models for lethal infection and antiviral treatment. The viral neuraminidases...

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Bibliografiska uppgifter
Huvudupphovsmän: Smee, Donald F., Julander, Justin G., Tarbet, E. Bart, Gross, Matthew, Nguyen, Jack
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465485/
https://ncbi.nlm.nih.gov/pubmed/22809862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2012.07.002
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