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Treatment of Oseltamivir-Resistant Influenza A (H1N1) Virus Infections in Mice With Antiviral Agents

Influenza A/Mississippi/03/2001 (H1N1) and A/Hong Kong/2369/2009 (H1N1) viruses containing the neuraminidase gene mutation H275Y (conferring resistance to oseltamivir) were adapted to mice and evaluated for suitability as models for lethal infection and antiviral treatment. The viral neuraminidases...

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Detalhes bibliográficos
Main Authors: Smee, Donald F., Julander, Justin G., Tarbet, E. Bart, Gross, Matthew, Nguyen, Jack
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465485/
https://ncbi.nlm.nih.gov/pubmed/22809862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2012.07.002
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