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Revisiting the contribution of negative charges on the chaperonin cage wall to the acceleration of protein folding
Chaperonin GroEL mediates the folding of protein encapsulated in a GroES-sealed cavity (cage). Recently, a critical role of negative charge clusters on the cage wall in folding acceleration was proposed based on experiments using GroEL single-ring (SR) mutants SR1 and SRKKK2 [Tang YC, et al. (2006)...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3465421/ https://ncbi.nlm.nih.gov/pubmed/22961256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1204547109 |
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