Use of chimeric proteins to investigate the role of transporter associated with antigen processing (TAP) structural domains in peptide binding and translocation

The transporter associated with antigen processing (TAP) comprises two subunits, TAP1 and TAP2, each containing a hydrophobic membrane-spanning region (MSR) and a nucleotide binding domain (NBD). The TAP1/TAP2 complex is required for peptide translocation across the endoplasmic reticulum membrane. T...

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Bibliographic Details
Main Authors: Arora, Shikha, Lapinski, Philip Edward, Raghavan, Malini
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2001
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC34653/
https://ncbi.nlm.nih.gov/pubmed/11416206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.131132198
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