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Analyses of Conformational States of the Transporter Associated with Antigen Processing (TAP) Protein in a Native Cellular Membrane Environment

The transporter associated with antigen processing (TAP) plays a critical role in the MHC class I antigen presentation pathway. TAP translocates cellular peptides across the endoplasmic reticulum membrane in an ATP hydrolysis-dependent manner. We used FRET spectroscopy in permeabilized cells to deli...

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Autori principali: Geng, Jie, Sivaramakrishnan, Sivaraj, Raghavan, Malini
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873560/
https://ncbi.nlm.nih.gov/pubmed/24196954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.504696
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