Plasma Uric Acid Levels Correlate with Inflammation and Disease Severity in Malian Children with Plasmodium falciparum Malaria

BACKGROUND: Plasmodium falciparum elicits host inflammatory responses that cause the symptoms and severe manifestations of malaria. One proposed mechanism involves formation of immunostimulatory uric acid (UA) precipitates, which are released from sequestered schizonts into microvessels. Another inv...

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Detalhes bibliográficos
Main Authors: Lopera-Mesa, Tatiana M., Mita-Mendoza, Neida K., van de Hoef, Diana L., Doumbia, Saibou, Konaté, Drissa, Doumbouya, Mory, Gu, Wenjuan, Traoré, Karim, Diakité, Seidina A. S., Remaley, Alan T., Anderson, Jennifer M., Rodriguez, Ana, Fay, Michael P., Long, Carole A., Diakité, Mahamadou, Fairhurst, Rick M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465329/
https://ncbi.nlm.nih.gov/pubmed/23071567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046424
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