Heterogeneity in White Blood Cells Has Potential to Confound DNA Methylation Measurements

Epigenetic studies are commonly conducted on DNA from tissue samples. However, tissues are ensembles of cells that may each have their own epigenetic profile, and therefore inter-individual cellular heterogeneity may compromise these studies. Here, we explore the potential for such confounding on DN...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Adalsteinsson, Bjorn T., Gudnason, Haukur, Aspelund, Thor, Harris, Tamara B., Launer, Lenore J., Eiriksdottir, Gudny, Smith, Albert V., Gudnason, Vilmundur
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2012
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465258/
https://ncbi.nlm.nih.gov/pubmed/23071618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046705
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