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Formulation and optimization of mucoadhesive bilayer buccal tablets of atenolol using simplex design method

INTRODUCTION: In the present study, mucoadhesive buccal bilayer tablets of atenolol were fabricated with the objective of avoiding first pass metabolism and to improve its bioavailability with reduction in dosing frequency. Hence, the aim of this work was to design oral controlled release mucoadhesi...

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Detalhes bibliográficos
Main Authors: Shirsand, SB, Suresh, Sarasija, Keshavshetti, GG, Swamy, PV, Reddy, P Vijay Prakash
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465156/
https://ncbi.nlm.nih.gov/pubmed/23071958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2230-973X.96924
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