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Study on sustained-release metformin hydrochloride from matrix tablet: Influence of hydrophilic polymers and in vitro evaluation

The overall objective of the present work was to develop an oral sustained-release (SR) metformin tablet prepared by the direct compression method, using hydrophilic hydroxylpropylmethylcellulose (HPMC) and Guar gum polymer alone and in combination at different concentrations. Metformin hydrochlorid...

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Autors principals: Wadher, Kamlesh J, Kakde, Rajendra B, Umekar, Milind J
Format: Artigo
Idioma:Inglês
Publicat: Medknow Publications & Media Pvt Ltd 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465141/
https://ncbi.nlm.nih.gov/pubmed/23071938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2230-973X.85966
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