Significant pharmacokinetic interactions between artemether/lumefantrine and efavirenz or nevirapine in HIV-infected Ugandan adults

OBJECTIVES: Co-administration of artemether/lumefantrine with antiretroviral therapy has potential for pharmacokinetic drug interactions. We investigated drug–drug interactions between artemether/lumefantrine and efavirenz or nevirapine. METHODS: We performed a cross-over study in which HIV-infected...

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Bibliographic Details
Main Authors: Byakika-Kibwika, Pauline, Lamorde, Mohammed, Mayito, Jonathan, Nabukeera, Lillian, Namakula, Rhoda, Mayanja-Kizza, Harriet, Katabira, Elly, Ntale, Muhammad, Pakker, Nadine, Ryan, Mairin, Hanpithakpong, Warunee, Tarning, Joel, Lindegardh, Niklas, de Vries, Peter J., Khoo, Saye, Back, David, Merry, Concepta
Format: Artigo
Language:Inglês
Published: Oxford University Press 2012
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465101/
https://ncbi.nlm.nih.gov/pubmed/22687893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dks207
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