Elevated type I interferon-like activity in a subset of multiple sclerosis patients: molecular basis and clinical relevance

BACKGROUND: A subset of patients with multiple sclerosis (MS) shows an increased endogenous IFN-like activity before initiation of IFN-beta treatment. The molecular basis of this phenomenon and its relevance to predict individual therapy outcomes are not yet fully understood. We studied the expressi...

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Main Authors: Hundeshagen, Alexander, Hecker, Michael, Paap, Brigitte Katrin, Angerstein, Charlotte, Kandulski, Ole, Fatum, Christian, Hartmann, Christiane, Koczan, Dirk, Thiesen, Hans-Juergen, Zettl, Uwe Klaus
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464734/
https://ncbi.nlm.nih.gov/pubmed/22727118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-140
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