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Specific recognition of the product of a transferred major histocompatibility complex gene by cytotoxic T lymphocytes.

Mouse L cells transfected with a genomic clone containing the H-2Ld gene (8-5 cells) were shown to function as targets for H-2Ld-specific cytotoxic T lymphocytes (CTL). The CTL-mediated lysis of 8-5 cells was shown to be H-2Ld specific by the use of (i) CTL with restricted reactivity, (ii) unlabeled...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Woodward, J G, Orn, A, Harmon, R C, Goodenow, R S, Hood, L, Frelinger, J A
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1982
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346473/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6980415/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.11.3613
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