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Major histocompatibility complex class I-specific and -restricted killing of beta 2-microglobulin-deficient cells by CD8+ cytotoxic T lymphocytes.

Cytotoxic T lymphocytes (CTLs) recognize major histocompatibility complex (MHC) class I molecules, normally composed of a heavy chain, a beta 2-microglobulin (beta 2m), and peptide antigens. beta 2m is considered essential for the assembly and intracellular transport of MHC class I molecules as well...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Glas, R, Franksson, L, Ohlén, C, Höglund, P, Koller, B, Ljunggren, H G, Kärre, K
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50554/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1454824/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.23.11381
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