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Identification and characterization of a lysosomal transporter for small neutral amino acids

In eukaryotic cells, lysosomes represent a major site for macromolecule degradation. Hydrolysis products are eventually exported from this acidic organelle into the cytosol through specific transporters. Impairment of this process at either the hydrolysis or the efflux step is responsible of several...

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Main Authors: Sagné, Corinne, Agulhon, Cendra, Ravassard, Philippe, Darmon, Michèle, Hamon, Michel, El Mestikawy, Salah, Gasnier, Bruno, Giros, Bruno
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC34647/
https://ncbi.nlm.nih.gov/pubmed/11390972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.121183498
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