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Effect of dose fractionation on the ethylnitrosourea induction of specific-locus mutations in mouse spermatogonia.
As measured by specific-locus mutations in mouse spermatogonia, fractionating a dose of 100 mg of ethylnitrosourea per kg of body weight into doses of 10 mg/kg injected intraperitoneally at weekly intervals greatly reduces the mutation frequency compared with that from a single dose of 100 mg/kg. Be...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
1982
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346468/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6954506/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.11.3592 |
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