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Effect of dose fractionation on the ethylnitrosourea induction of specific-locus mutations in mouse spermatogonia.

As measured by specific-locus mutations in mouse spermatogonia, fractionating a dose of 100 mg of ethylnitrosourea per kg of body weight into doses of 10 mg/kg injected intraperitoneally at weekly intervals greatly reduces the mutation frequency compared with that from a single dose of 100 mg/kg. Be...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Russell, W L, Hunsicker, P R, Carpenter, D A, Cornett, C V, Guinn, G M
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1982
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346468/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6954506/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.11.3592
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