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Effect of dose fractionation on the ethylnitrosourea induction of specific-locus mutations in mouse spermatogonia.

As measured by specific-locus mutations in mouse spermatogonia, fractionating a dose of 100 mg of ethylnitrosourea per kg of body weight into doses of 10 mg/kg injected intraperitoneally at weekly intervals greatly reduces the mutation frequency compared with that from a single dose of 100 mg/kg. Be...

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Detalhes bibliográficos
Main Authors: Russell, W L, Hunsicker, P R, Carpenter, D A, Cornett, C V, Guinn, G M
Formato: Artigo
Idioma:Inglês
Publicado em: 1982
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC346468/
https://ncbi.nlm.nih.gov/pubmed/6954506
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