Expression of protein-tyrosine phosphatases in Acute Myeloid Leukemia cells: FLT3 ITD sustains high levels of DUSP6 expression

Protein-tyrosine phosphatases (PTPs) are important regulators of cellular signaling and changes in PTP activity can contribute to cell transformation. Little is known about the role of PTPs in Acute Myeloid Leukemia (AML). The aim of this study was therefore to establish a PTP expression profile in...

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Main Authors: Arora, Deepika, Köthe, Susanne, van den Eijnden, Monique, van Huijsduijnen, Rob Hooft, Heidel, Florian, Fischer, Thomas, Scholl, Sebastian, Tölle, Benjamin, Böhmer, Sylvia-Annette, Lennartsson, Johan, Isken, Fabienne, Müller-Tidow, Carsten, Böhmer, Frank-D
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464674/
https://ncbi.nlm.nih.gov/pubmed/22784513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-811X-10-19
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